منابع مشابه
Aquaporins
and take over the discipline. If we want to make sure that the biology of the future preserves our hard-won biological perspectives, knowledge and insights, we need to be able to do the analyses and deal with all these data ourselves. For young scientists embarking on a PhD, make sure your PhD topic is something you love, and that your question is one whose answer you care deeply about. Don’t s...
متن کاملIncipient Balancing Selection through Adaptive Loss of Aquaporins in Natural Saccharomyces cerevisiae Populations
A major goal in evolutionary biology is to understand how adaptive evolution has influenced natural variation, but identifying loci subject to positive selection has been a challenge. Here we present the adaptive loss of a pair of paralogous genes in specific Saccharomyces cerevisiae subpopulations. We mapped natural variation in freeze-thaw tolerance to two water transporters, AQY1 and AQY2, p...
متن کاملAquaporins in Saccharomyces: Characterization of a second functional water channel protein.
The Saccharomyces cerevisiae genome database contains two ORFs with homology to aquaporins, AQY1 and AQY2. Aqy1p has been shown to be a functional aquaporin in some strains, such as Sigma1278b. AQY2 is disrupted by a stop codon in most strains; however, Sigma1278b has an intact ORF. Because Sigma1278b Aqy2p has an intracellular localization in Xenopus oocytes and in yeast, other strains of yeas...
متن کاملAquaporins in plants.
Although very often exposed to a rapid changing environment, plants are in general unable to evade from unfavourable conditions. Therefore, a fine tuned adaptation of physiology including the water balance appears to be of crucial importance. As a consequence a relatively large number of aquaporin genes are present in plant genomes. So far aquaporins in plants were shown to be involved in root ...
متن کاملAquaporins in the Kidney
Water is a major component of the cell, forming between 70 and 95% of its mass. It can cross lipid bilayers of all biological membranes by simple diffusion. However, diffusion is a slow, non-regulated process which cannot account for selective transmembrane water permeation as occurs in many fluid transporting tissues during normal physiological processes. This suggested the existence of additi...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1998
ISSN: 0021-9258
DOI: 10.1074/jbc.273.42.27565